the short answer
For most clients, cardio does not kill gains. The interference effect, where lots of endurance work slightly dampens strength and muscle gains, is real but modest and manageable. It mostly shows up with high volumes of hard cardio done close to the muscles you are growing. Keep cardio mostly easy, low-impact and separate from heavy leg training.
Keeping cardio's value in view helps: the World Health Organization recommends adults get at least 150 minutes of moderate-intensity physical activity per week. The WHO also states that "muscle strengthening benefits everyone", which is exactly why the aim is to keep lifting central and let cardio complement it rather than replace it.
This article is general coaching information, not medical advice - individual needs vary, and any client with a heart, lung, or other medical condition, or signs of overtraining, should be referred to a doctor before changing their training load.